JL
Publications
- Transformation of mature mouse B cells into malignant plasma cells in vitro via introduction of defined genetic elements.
- Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis.
- Array profiling reveals contribution of Cthrc1 to growth of the denervated rat urinary bladder.
- The Mastery Rubric for Bioinformatics: supporting design and evaluation of career-spanning education and training
- Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival.
- Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy.
- ELIXIR training quality & impact assessment strategy status
- Introducing the The Mastery Rubric for Bioinformatics – a Professional Guide
- NBIS Training Report 2020 – 2021
- Using the The Mastery Rubric for Bioinformatics – A professional guide
- Hypoxia inducible factor‐2α importance for migration, proliferation, and self‐renewal of trunk neural crest cells
- An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.
- Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy.
- DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.
- The Oct1 homolog Nubbin is a repressor of NF-kappaB-dependent immune gene expression that increases the tolerance to the gut microbiota.
- Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1.
- Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.
- Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid.
- Differential evolutionary wiring of the tyrosine kinase Btk.
- A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
- Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents.
- A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.
- Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides.
- Custom design and analysis of high-density oligonucleotide bacterial tiling microarrays.
- Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells.
- Expression profiling of chicken DT40 lymphoma cells indicates clonal selection of knockout and gene reconstituted cells.
- Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9.
- Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.
- Gene expression signatures in primary immunodeficiencies: the experience from human disease and mouse models.
- Distinct gene expression signature in Btk-defective T1 B-cells.
- Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells.
- Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.
- Gene expression profile of B cells from Xid mice and Btk knockout mice.
- In silico tools for signal transduction research.
- High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.
- Interaction of Btk and Akt in B cell signaling.
- Expression profiling in transformed human B cells: influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays.
- Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response.
- A microarray whole-genome gene expression dataset in a rat model of inflammatory corneal angiogenesis.
- Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes.
- In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8+ T cells--A Tool to Interrogate a Functional Immune Response Ex Vivo.
- Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients.
- Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.
- The effect of interior aircraft noise on pilot performance.