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Single-cell ATAC sequencing data from: Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases

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posted on 2025-01-29, 08:25 authored by Hanna ThorssonHanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Ludvig Sjöström, Helena Ågerstam, Pablo Peña-Martínez, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Vibeke Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

This dataset contains single-cell ATAC sequencing data from nineteen cases of childhood BCP-ALL and four samples of mononuclear cells from normal bone marrow from healthy donors. The dataset is available as raw sequencing reads (fastq; restricted access) or as an annotated ATAC dataset (h5ad). The libraries were prepared according to the manufacturer’s instructions (10x Genomics CG000169: Nuclei Isolation for Single Cell ATAC Sequencing; 10x Genomics CG000209: Chromium Single Cell ATAC Reagent Kits v1.1).) and sequenced on a Novaseq 6000.

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Lund University

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    Thoas Fioretos Lab

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