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RNA sequencing data from: Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia

dataset
posted on 2025-05-16, 12:06 authored by Carl SandénCarl Sandén, Henrik LilljebjörnHenrik Lilljebjörn, Thoas Fioretos

This dataset includes RNA sequencing (RNA-seq) data from the HNT-34 AML (acute myeloid leukemia) cell line after knockout of the SLAMF6 gene by CRISPR/Cas9 (SLAMF6-KO) or mock-knockout with a construct targeting the firefly luciferase gene (SLAMF6-WT). Libraries were produced using the Illumina stranded mRNA prep kit and sequenced on an Illumina Novaseq 6000 system (Illumina). The dataset is available as raw sequencing reads (fastq.bz2) or as merged transcripts per million (TPM) data for all cases generated using Salmon (salmon.merged.gene_tpm.tsv.gz).

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Lund University

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    Thoas Fioretos Lab

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