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.IBD
6-ohda-_striatum_lipids_negative-rms.ibd (268.87 MB)
.IMZML
6-ohda-_striatum_lipids_negative-rms.imzML (94.68 MB)
.IBD
psap_4month_8month_striatum_neurotransmitters_positive-rms.ibd (2.57 GB)
.IMZML
psap_4month_8month_striatum_neurotransmitters_positive-rms.imzML (168.89 MB)
.IBD
psap_4month_cerebellum_lipids_negative-rms.ibd (223.83 MB)
.IMZML
psap_4month_cerebellum_lipids_negative-rms.imzML (76.09 MB)
.IBD
psap_4month_cerebellum_lipids_positive-rms.ibd (285.84 MB)
.IMZML
psap_4month_cerebellum_lipids_positive-rms.imzML (76.1 MB)
.IBD
psap_4month_sn_lipids_negative-rms.ibd (1.12 GB)
.IMZML
psap_4month_sn_lipids_negative-rms.imzML (84.88 MB)
.IBD
psap_4month_sn_lipids_positive-rms.ibd (1021.91 MB)
.IMZML
psap_4month_sn_lipids_positive-rms.imzML (84.87 MB)
.IBD
psap_4month_sn_neurotransmitters_positive-rms.ibd (1.46 GB)
.IMZML
psap_4month_sn_neurotransmitters_positive-rms.imzML (92.27 MB)
.IBD
psap_4month_striatum_lipids_negative-rms.ibd (842.4 MB)
.IMZML
psap_4month_striatum_lipids_negative-rms.imzML (61.35 MB)
.IBD
psap_4month_striatum_lipids_positive-rms.ibd (730.88 MB)
.IMZML
psap_4month_striatum_lipids_positive-rms.imzML (61.35 MB)
.IBD
psap_8month_sn_lipids_negative-rms.ibd (996.51 MB)
.IMZML
psap_8month_sn_lipids_negative-rms.imzML (80.73 MB)
1/0
60 files

Lipids and Neurotransmitters Mass Spectrometry Imaging Data from Dopaminergic PSAP Deficient (cPSAPDAT) and Serotonergic PSAP deficient (cPSAPSERT) Mice Brain Tissue sections

dataset
posted on 2023-08-11, 12:10 authored by Ibrahim KayaIbrahim Kaya, Anna Nilsson, Reza Shariatgorji, Per E. Andren

The files above are MALDI-MSI (Matrix Assisted Laser Desorption Ionization - Mass Spectrometry Imaging) experiments. The dataset contains both imzML, which is the common MSI open file type containing x, y positions in tissue as well as m/z and intensity, which is a more user friendly format. The data contained in this dataset should be enough to recreate the MSI parts of the manuscript.

Prosaposin (PSAP) modulates glycosphingolipid metabolism and may relate to Parkinson’s disease (PD). Here, the lipids and neurotransmitters MALDI-MSI data have been collected from dopaminergic PSAP-deficient (cPSAPDAT) mice and serotonergic PSAP-deficient (cPSAPSERT) mice as well as 6-OHDA-induced Parkinson's disease mouse model.


For any questions about the dataset or to request access to any files not uploaded here, please contact per.andren@uu.se

Funding

Vetenskapsrådet (Swedish Research Council) - 2022-04198

Hjärnfonden (Swedish Brain Foundation) - FO2021-0318

History

Publisher

Science for Life Laboratory, Sweden

Contact email

per.andren@uu.se

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