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Immunoglobulin M and immunoglobulin G repertoire sequencing data of two donors first infected with SARS-CoV-2 then vaccinated with mRNA-1273
Immunoglobulin M (IgM) and immunoglobulin G (IgG) repertoire sequencing libraries from two donors who were first infected by index SARS-CoV-2, then vaccinated by the mRNA-1273 vaccine. We acquired longitudinal peripheral blood mononuclear cells (PBMCs) samples from each respective donor as follows: 11 or 14 days post-infection (acute timepoint), 32 or 37 days post-infection (convalescent timepoint), 160 or 169 days post-infection (pre-vax timepoint), and 9 or 7 days post-vaccination (post-vax timepoint). Three IgM libraries were generated from each donor for the Acute timepoint, as well as one IgG library per timepoint per donor for a total of 6 IgM and 6 IgG Rep-seq libraries.
SciLifeLab National COVID-19 Research Program (C19VE:G:007)
Knut and Alice Wallenberg Foundation
Genetic basis for antibody diversity
Swedish Research CouncilFind out more...