GSEA/GSVA-based Analysis of Primary Breast Tumors with/without Recurrence

GSEA comparsion between primary breast tumors with a matched recurrence (S sample, n = 27) and tumors with no recurrence (V samples, n = 21). GSEA output is provided for RNA and protein mass spectrometry data (database: HALLMARKS). GSVA scores for key enriched pathways (E2F targets and allograft rejection) are provided too along with immunohistochemical analysis of poliferation marker Ki-67 and leukocyte counts.

This dataset was used for Figure 6 in the following manuscript:

 "Proteogenomics decodes the evolution of human ipsilateral breast cancer". De Marchi T, Pyl PT, Sjöström M, Reinsbach SE, DiLorenzo S, Nystedt B, Tran L, Pekar G, Wärnberg F, Fredriksson I, Malmström P, Fernö M, Malmström L, Malmström J, Nimèus E. accepted for publication