Data for 'An interactive web resource for exploring equine BAL cell scRNA-seq data'

This dataset contains the count matrices required to reproduce the web application for interactive visualization of single-cell RNA-seq (scRNA-seq) data from equine bronchoalveolar lavage (BAL) cells. The Shiny app is available at: https://equbal-explorer.serve.scilifelab.se/app/equbal-explorer hosted by SciLifeLab serve. The web application can be recreated using the scripts provided in the associated GitHub repository: https://github.com/Molmed/EquBAL_explorer.

The scRNA-seq data were generated from 21 clinical equine asthma cases and 8 healthy controls using the HIVE and Drop-seq platforms. Details of the laboratory procedures and the generation of the count matrices are described in the original publications: https://doi.org/10.1038/s41598-023-43368-4 and https://doi.org/10.1371/journal.pone.0317343. Raw sequencing data is available at SRA as described in these papers.

A phenotype file is also provided, containing BAL cytology and other phenotypic information for the samples included in the web application.